Article
Mutations of ras genes are relatively frequent in Japanese prostate cancers: pointing to genetic differences between populations.
Anticancer research - 1 Jan 2000
Shiraishi T, Muneyuki T, Fukutome K, Ito H, Kotake T, Watanabe M, Yatani R
Abstract excerpt
Point mutations of the ras gene family are thought to be involved in the development of a variety of human tumors. However, it remains unknown whether the ras gene might play a key role in prostate carcinogenesis. We therefore analysed Ki-,N- and H-ras gene mutations in a series of 81 Japanese prostate cancers using PCR-SSCP analysis and Mutant-Allele-Specific Amplification (MASA) method. Mutated as genes were...
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