Article
Presence of ras oncogene mutations and human papillomavirus DNA in human prostate carcinomas.
Cancer research - 1 Nov 1992
Anwar K, Nakakuki K, Shiraishi T, Naiki H, Yatani R, Inuzuka M
Abstract excerpt
The frequency of H-ras, K-ras, and N-ras mutations and the presence of high-risk human papillomavirus (HPV 16, 18, and 33) DNA were studied in 75 paraffin-embedded specimens obtained from 68 Japanese patients with a variety of prostate carcinomas by using polymerase chain reaction and DNA hybridization with sequence-specific oligonucleotides. Ten specimens each of normal and benign hyperplastic prostatic tissues...
Topics
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- DNA, Viral
- Genes, ras
- Humans
- Japan
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Papillomaviridae
