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Article

Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1.

Mechanisms of development - 1 Apr 2005

Etard Christelle, Gradl Dietmar, Kunz Martin, Eilers Martin, Wedlich Doris

Abstract excerpt

Pontin (Tip49) and Reptin (Tip48) are highly conserved components of multimeric protein complexes important for chromatin remodelling and transcription. They interact with many different proteins including TATA box binding protein (TBP), beta-catenin and c-Myc and thus, potentially modulate different pathways. As antagonistic regulators of Wnt-signalling, they control wing development in Drosophila and heart...

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Source

Identifiers

PMID: 15804567
DOI: 10.1016/j.mod.2004.11.010

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1.PMID 15804567Read ↗

Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.Semantic proximity Read ↗

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Miz1 is required for early embryonic development during gastrulation.Semantic proximity Read ↗

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