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Article

Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype.

Proceedings of the National Academy of Sciences of the United States of America - 18 Feb 1997

Schreiber-Agus N, Stein D, Chen K, Goltz J S, Stevens L, DePinho R A

Abstract excerpt

Biochemical and biological activities of Myc oncoproteins are highly dependent upon their association with another basic region helix-loop-helix/leucine zipper (bHLH/LZ) protein, Max. Our previous observation that the DNA-binding/dimerization region of Max is absolutely conserved throughout vertebrate evolution provided the basis for a yeast two-hybrid interaction screen that led to the isolation of the...

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Identifiers

PMID: 9037036
DOI: 10.1073/pnas.94.4.1235
PMCID: PMC19774

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Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype.PMID 9037036Read ↗

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