Article
Candidate gene susceptibility variants predict intermediate end points but not angiographic coronary artery disease.
American heart journal - 1 Aug 2005
Whiting Bryant M, Anderson Jeffrey L, Muhlestein Joseph B, Horne Benjamin D, Bair Tami L, Pearson Robert R, Carlquist John F
Abstract excerpt
BACKGROUND: Moderate-sized studies have suggested that variants of candidate genes can influence laboratory markers of coronary artery disease (CAD), but whether they predict parallel changes in clinical CAD risk is unknown. METHODS: We studied a single nucleotide polymorphism (SNP) from each of the 5 candidate genes for intermediate (laboratory) and clinical (angiographic CAD) end points in a large cohort of...
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