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Article

Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes.

Journal of medical genetics - 1 May 2004

McCarthy J J, Parker A, Salem R, Moliterno D J, Wang Q, Plow E F, Rao S, Shen G, Rogers W J, Newby L K, Cannata R, Glatt K, Topol E J

Abstract excerpt

BACKGROUND: to date, only three groups have reported data from large scale genetic association studies of coronary heart disease using a case control design. METHODS AND RESULTS: to extend our initial report of 62 genes, we present data for 210 polymorphisms in 111 candidate genes genotyped in 352 white subjects with familial, premature coronary heart disease (onset age for men, 45; for women, 50) and a random...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15121769
DOI: 10.1136/jmg.2003.016584
PMCID: PMC1579684

Genes

THBS4
THBS2
ACE
APOE
FGB
LRP1
MTHFR
SELP
THPO

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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