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Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women

1 Aug 2005

Abstract excerpt

OBJECTIVE: Postmenopausal estradiol (E(2)) levels vary widely between individuals and this variation is an important determinant of diseases such as osteoporosis. It has been suggested that the estrogen receptor alpha (ESR1) gene may influence peripheral E(2) levels, but the role of common sequence variations in the ESR1 gene is unclear. METHODS: In 631 postmenopausal women and 528 men from the Rotterdam Study, a...

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PMID: 16061840
DOI: 10.1530/eje.1.01973

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Source receipt: pubmed, retrieved 7 Sept 2026.

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