Article
ESR1 and ESR2 gene polymorphisms are associated with human reproduction outcomes in Brazilian women.
Journal of ovarian research - 20 Dec 2014
de Mattos Clarissa Santiago, Trevisan Camila Martins, Peluso Carla, Adami Fernando, Cordts Emerson Barchi, Christofolini Denise Maria, Barbosa Caio Parente, Bianco Bianca
Abstract excerpt
BACKGROUND: Important candidate genes involved in the ovarian response to exogenous FSH are the estrogen receptor genes (ESRs), since the effects of estrogens on follicle growth, maturation and oocyte release. It is known that some markers of ovarian stimulation can help to personalize the treatment, adjusting the dose of exogenous rFSH, thus preventing excessive wear of the patient. Inspired on this information...
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