Article
Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk.
Breast cancer research and treatment - 1 Feb 2008
González-Zuloeta Ladd A M, Vásquez A Arias, Rivadeneira F, Siemes C, Hofman A, Stricker B H Ch, Pols H A P, Uitterlinden A G, van Duijn C M
Abstract excerpt
BACKGROUND: The estrogen receptor alpha (ESR1) is a mediator of estrogen response in the breast. The most studied variants in this gene are the PvuII and XbaI polymorphisms, which have been associated to lower sensitivity to estrogen. We evaluated whether these polymorphisms were associated with...
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