Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk

1 Jul 2003

Abstract excerpt

This study investigates the influence of genetic variation of the estrogen receptor alpha (ESR1) gene locus on several bone parameters in 2042 individuals of The Rotterdam Study, a prospective population-based cohort study of elderly subjects. We analysed three polymorphic sites in the 5' region of the ESR1 gene; a (TA)(n)-repeat in the promoter region, and molecular haplotypes of the PvuII and XbaI RFLPs in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and osteoporosis research
Share to Bone Metabolism and Diseases
Share to Estrogen and related hormone effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12837697
DOI: 10.1093/hmg/ddg176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture riskPMID 12837697Read ↗

Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes.Semantic proximity Read ↗

Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor alpha gene and their relationship to bone mass variation in postmenopausal Italian women.Semantic proximity Read ↗

Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis.Semantic proximity Read ↗

Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis.Semantic proximity Read ↗

Association of oestrogen receptor alpha gene polymorphisms with postmenopausal bone loss, bone mass, and quantitative ultrasound properties of bone.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphisms and bone mineral density: haplotype analysis in women from the United Kingdom.Semantic proximity Read ↗

Haplotypes of intron 4 of the estrogen receptor alpha gene and hip fractures: a replication study in Caucasians.Semantic proximity Read ↗

Estrogen receptor beta polymorphisms are associated with bone mass in women and men: the Framingham Study.Semantic proximity Read ↗

Association of estrogen receptor alpha gene polymorphisms with bone mineral density: a meta-analysis.Semantic proximity Read ↗

Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women.Semantic proximity Read ↗

Association of estrogen receptor alpha gene polymorphisms with bone mineral density in Chinese women: a meta-analysis.Semantic proximity Read ↗

Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.