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Article

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2005

Wang YongJun, Belflower Ruth M, Dong Yu-Feng, Schwarz Edward M, O'Keefe Regis J, Drissi Hicham

Abstract excerpt

UNLABELLED: Runx proteins mediate skeletal development. We studied the regulation of Runx1 during chondrocyte differentiation by real-time RT-PCR and its function during chondrogenesis using overexpression and RNA interference. Runx1 induces mesenchymal stem cell commitment to the early stages of chondrogenesis. INTRODUCTION: Runx1 and Runx2 are co-expressed in limb bud cell condensations that undergo both...

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Source

Identifiers

PMID: 16059634
DOI: 10.1359/JBMR.050516

Genes

BMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.PMID 16059634Read ↗

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