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Transcriptional Regulatory Cascades in Runx2-Dependent Bone Development

14 Nov 2012

Abstract excerpt

The development of the musculoskeletal system is a complex process that involves very precise control of bone formation and growth as well as remodeling during postnatal life. Although the understanding of the transcriptional mechanisms of osteogenesis has increased considerably, the molecular regulatory basis, especially the gene regulatory network of osteogenic differentiation, is still poorly understood. This...

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PMID: 23150948
DOI: 10.1089/ten.teb.2012.0527

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