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Article

Role of Runx genes in chondrocyte differentiation.

Developmental biology - 1 May 2002

Stricker Sigmar, Fundele Reinald, Vortkamp Andrea, Mundlos Stefan

Abstract excerpt

Runx2/Cbfa1 plays a central role in skeletal development as demonstrated by the absence of osteoblasts/bone in mice with inactivated Runx2/Cbfa1 alleles. To further investigate the role of Runx2 in cartilage differentiation and to assess the potential of Runx2 to induce bone formation, we cloned chicken Runx2 and overexpressed it in chick embryos using a retroviral system. Infected chick wings showed multiple...

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Identifiers

PMID: 11969258
DOI: 10.1006/dbio.2002.0640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Role of Runx genes in chondrocyte differentiation.PMID 11969258Read ↗

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