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Article

Runx3/AML2/Cbfa3 Regulates Early and Late Chondrocyte Differentiation

8 May 2007

Abstract excerpt

UNLABELLED: We studied the expression and function of Runx3 during chondrogenesis and chondrocyte maturation. We found that Runx3 is essential for mediating the early stage of endochondral ossification through cooperation with other Runx family members. INTRODUCTION: Runx proteins are spatially and temporally co-expressed during skeletal formation. A cooperative and/or redundant function between these factors was...

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Identifiers

PMID: 17488194
DOI: 10.1359/jbmr.070502

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