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Article

Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype.

Molecular and cellular biology - 1 Aug 2005

Putnam Christopher D, Pennaneach Vincent, Kolodner Richard D

Abstract excerpt

Translocations, deletions, and chromosome fusions are frequent events seen in cancers with genome instability. Here we analyzed 358 genome rearrangements generated in Saccharomyces cerevisiae selected by the loss of the nonessential terminal segment of chromosome V. The rearrangements appeared to be generated by both nonhomologous end joining and homologous recombination and targeted all chromosomes. Fifteen...

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Share to Chromosomal Instability
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16055731
DOI: 10.1128/MCB.25.16.7226-7238.2005
PMCID: PMC1190249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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