Different aneuploidies arise from the same bridge-induced chromosomal translocation event in Saccharomyces cerevisiae.

Abstract excerpt

Chromosome translocations are gross chromosomal rearrangements that have often been associated with cancer development in mammalian cells. The feasibility of drastically reshaping the genome with a single translocation event also gives this molecular event a powerful capacity to drive evolution. Despite these implications and their role in genome instability, very little is known about the molecular mechanisms...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aneuploidy
• Share to Chromosomes, Fungal
• Share to DNA, Fungal