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Article

A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements.

PLoS genetics - 1 May 2011

Chan Jason E, Kolodner Richard D

Abstract excerpt

Ty elements are high copy number, dispersed repeated sequences in the Saccharomyces cerevisiae genome known to mediate gross chromosomal rearrangements (GCRs). Here we found that introduction of Ty912, a previously identified Ty1 element, onto the non-essential terminal region of the left arm of chromosome V led to a 380-fold increase in the rate of accumulating GCRs in a wild-type strain. A survey of 48...

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Identifiers

PMID: 21637792
DOI: 10.1371/journal.pgen.1002089
PMCID: PMC3102749

Genes

RAD52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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