Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling colorectal cancer evolution.

Journal of human genetics - 1 Sept 2021

Niida Atsushi, Mimori Koshi, Shibata Tatsuhiro, Miyano Satoru

Abstract excerpt

Understanding cancer evolution provides a clue to tackle therapeutic difficulties in colorectal cancer. In this review, together with related works, we will introduce a series of our studies, in which we constructed an evolutionary model of colorectal cancer by combining genomic analysis and mathematical modeling. In our model, multiple subclones were generated by driver mutation acquisition and subsequent clonal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Cancer Genomics and Diagnostics
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Evolution and Genetic Dynamics

Share to Genetic factors in colorectal cancer

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 33986478
DOI: 10.1038/s10038-021-00930-0
PMCID: PMC8384629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling colorectal cancer evolution.PMID 33986478Read ↗

Cancer evolution and heterogeneitySemantic proximity Read ↗

The Evolutionary Landscape of Colorectal Tumorigenesis: Recent Paradigms, Models, and Hypotheses.Semantic proximity Read ↗

Tumour heterogeneity and evolutionary dynamics in colorectal cancerSemantic proximity Read ↗

Understanding intratumor heterogeneity by combining genome analysis and mathematical modelingSemantic proximity Read ↗

A unified simulation model for understanding the diversity of cancer evolutionSemantic proximity Read ↗

Unraveling the Drivers of Tumorigenesis in the Context of Evolution: Theoretical Models and Bioinformatics Tools.Semantic proximity Read ↗

New insights into the earliest stages of colorectal tumorigenesis.Semantic proximity Read ↗

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.Semantic proximity Read ↗

A new model of time scheme for progression of colorectal cancer.Semantic proximity Read ↗

Intratumor Heterogeneity and Evolution of Colorectal CancerSemantic proximity Read ↗

Evolutionary mechanisms and diversity in cancer.Semantic proximity Read ↗

An evolutionary model of carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.