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Article

Characterization of nuclear localization signals and cytoplasmic retention region in the nuclear receptor CAR.

Biochimica et biophysica acta - 10 Sept 2005

Kanno Yuichiro, Suzuki Motoyoshi, Nakahama Takayuki, Inouye Yoshio

Abstract excerpt

The constitutive androstane receptor (CAR) is a ligand/activator-dependent transactivation factor that resides in the cytoplasm and forms part of an as yet unidentified protein complex. Upon stimulation, CAR translocates into the nucleus where it modulates the transactivation of target genes. However, CAR exogenously expressed in rat liver RL-34 cells is located in the nucleus even in the absence of activators....

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Identifiers

PMID: 16055207
DOI: 10.1016/j.bbamcr.2005.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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