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Article

Role of NQO1 polymorphisms as risk factors for squamous cell carcinoma of the head and neck.

Oral oncology - 1 Oct 2005

Begleiter Asher, Norman Alia, Leitao Darren, Cabral Teresa, Hewitt Donna, Pan Sushu, Grandis Jennifer R, Siegfried Jill M, El-Sayed Samy, Sutherland Donna, Ross David A, Kerr Paul D

Abstract excerpt

A case: control study was carried out to determine if inactivating polymorphisms of the NQO1 gene at bases 609 and 465 are associated with altered risk of developing squamous cell carcinoma of the head and neck (SCCHN). Genotyping was carried out by PCR RFLP analysis on whole blood samples. The frequency of the inactive 609T and active 609C forms, and the inactive 465T and active 465C forms, of NQO1 were compared...

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Share to Carcinoma, Squamous Cell

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Share to NAD(P)H Dehydrogenase (Quinone)

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Source

Identifiers

PMID: 16054862
DOI: 10.1016/j.oraloncology.2005.05.004

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of NQO1 polymorphisms as risk factors for squamous cell carcinoma of the head and neck.PMID 16054862Read ↗

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