The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis.

doi:10.1038/bjc.2013.357

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Article

The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis.

British journal of cancer - 3 Sept 2013

Lajin B, Alachkar A

Abstract excerpt

BACKGROUND: Evidence is increasingly emerging about multiple roles for the NAD(P)H quinone oxidoreductase 1 enzyme in cancer. The C609T (rs1800566, Pro187Ser) null polymorphism of the NQO1 gene contributes significantly to the variation in enzymatic activity across different populations. NQO1 C60...

Topics

Female
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Humans
Male
NAD(P)H Dehydrogenase (Quinone)
Neoplasms
Polymorphism, Single Nucleotide
Risk Factors

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