Association of bladder cancer risk with an NAD(P)H:quinone oxidoreductase polymorphism in an ethnic Kashmiri population.

doi:10.1007/s10528-011-9418-8

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Article

Association of bladder cancer risk with an NAD(P)H:quinone oxidoreductase polymorphism in an ethnic Kashmiri population.

Biochemical genetics - 1 Aug 2011

Pandith Arshad A, Khan Nighat P, Shah Zafar A, Shah Amin M, Wani Saleem M, Siddiqi Mushtaq A

Abstract excerpt

NQO1 gene polymorphism at nucleotide 609 (Pro187Ser) results in a lowering of NQO1 detoxifying activity and is associated with susceptibility to various cancers. The NQO1 genotypes were identified by RFLP in 104 bladder cancer cases and 120 control subjects in an ethnic Kashmiri population. The f...

Topics

Aged
Alleles
Case-Control Studies
Ethnicity
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
India
Male
Middle Aged
NAD(P)H Dehydrogenase (Quinone)
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Risk Factors
Smoking
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 21253823
DOI: 10.1007/s10528-011-9418-8

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-21253823-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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