Article
Joint effect of smoking and NQO1 C609T polymorphism on undifferentiated nasopharyngeal carcinoma risk in a North African population.
Molecular genetics & genomic medicine - 1 Nov 2018
Moumad Khalid, Khaali Wafa, Benider Abdellatif, Ben Ayoub Wided, Hamdi-Cherif Mokhtar, Boualga Kada, Hassen Elham, Ben Driss El Khalil, Corbex Marilys, Khyatti Meriem
Abstract excerpt
BACKGROUND: Nasopharyngeal carcinoma (NPC) has a higher incidence in North Africa than in most parts of the world. In addition to environmental factors such as Epstein-Barr virus infection and chemical carcinogen exposure, genetic susceptibility has been reported to play a key role in the development of NPC. NAD(P)H: quinone oxidoreductase 1 is a cytosolic enzyme that protects cells from oxidative damage. A C to...
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