Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decoding dopamine signaling.

Cell - 29 Jul 2005

Bibb James A

Abstract excerpt

Dopamine is a key neurotransmitter that is important for many physiological functions including motor control, mood, and the reward pathway. In this issue of Cell, the laboratories of Marc Caron and Li-Huei Tsai identify two very different molecules--beta-arrestin 2 and Par-4, respectively--that unexpectedly are involved in dopamine signaling via the D2 receptor. These two new signaling pathways mediate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis Regulatory Proteins
Share to Arrestins
Share to beta-Arrestin 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Arrestins

Share to Dopamine

Share to Intracellular Signaling Peptides and Proteins

Share to Receptors, Dopamine D2

Share to Signal Transduction

Source

Identifiers

PMID: 16051141
DOI: 10.1016/j.cell.2005.07.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decoding dopamine signaling.PMID 16051141Read ↗

Getting specialized: presynaptic and postsynaptic dopamine D2 receptors.Semantic proximity Read ↗

The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation.Semantic proximity Read ↗

A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants.Semantic proximity Read ↗

Par-4 links dopamine signaling and depression.Semantic proximity Read ↗

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor.Semantic proximity Read ↗

Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors.Semantic proximity Read ↗

New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signalingSemantic proximity Read ↗

Translational profiling of mouse dopaminoceptive neurons reveals a role of PGE2 in dorsal striatumSemantic proximity Read ↗

Targeting arrestin interactions with its partners for therapeutic purposes.Semantic proximity Read ↗

Distinct regulation of internalization and mitogen-activated protein kinase activation by two isoforms of the dopamine D2 receptor.Semantic proximity Read ↗

Differential manipulation of arrestin-3 binding to basal and agonist-activated G protein-coupled receptors.Semantic proximity Read ↗

Mechanism of extrasynaptic dopamine signaling in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.