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Article

Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Jun 2012

Anzalone Andrea, Lizardi-Ortiz José E, Ramos Maria, De Mei Claudia, Hopf F Woodward, Iaccarino Ciro, Halbout Briac, Jacobsen Jacob, Kinoshita Chisato, Welter Marc, Caron Marc G, Bonci Antonello, Sulzer David, Borrelli Emiliana

Abstract excerpt

Dysfunctions of dopaminergic homeostasis leading to either low or high dopamine (DA) levels are causally linked to Parkinson's disease, schizophrenia, and addiction. Major sites of DA synthesis are the mesencephalic neurons originating in the substantia nigra and ventral tegmental area; these str...

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Identifiers

PMID: 22745501
DOI: 10.1523/JNEUROSCI.0918-12.2012
PMCID: PMC3752062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22745501-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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