Article
P-selectin glycoprotein ligand-1 variable number of tandem repeats (VNTR) polymorphism in patients with multiple sclerosis.
Neuroscience letters - 18 Nov 2005
Scalabrini Diego, Galimberti Daniela, Fenoglio Chiara, Comi Cristoforo, De Riz Milena, Venturelli Eliana, Castelli Luca, Piccio Laura, Ronzoni Marco, Lovati Carlo, Mariani Claudio, Monaco Francesco, Bresolin Nereo, Scarpini Elio
Abstract excerpt
P-selectin glycoprotein ligand-1 (PSGL-1) is an important adhesion molecule involved in lymphocyte recruitment into the brain, which represents a crucial step in the pathogenesis of multiple sclerosis (MS). Three hundred twenty-one MS patients and 342 controls were genotyped for the presence of a polymorphism in the PSGL-1 gene, consisting of a variable number of tandem repeats (VNTR) originating three possible...
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