Article
Short alleles of P-selectin glycoprotein ligand-1 protect against premature myocardial infarction.
American heart journal - 1 Oct 2004
Roldán Vanessa, González-Conejero Rocío, Marín Francisco, Pineda Javier, Vicente Vicente, Corral Javier
Abstract excerpt
BACKGROUND: Atherosclerosis is an inflammatory disease resulting from an injury that leads to an increase in the adhesiveness and permeability of the endothelium to leukocytes or platelets. The selectin family plays a key role initiating the cascade of events. Recently, we have demonstrated the functional relevance of a variable number of tandem repeats polymorphism affecting the P-selectin glycoprotein ligand...
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