Article
Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis.
Journal of neurology - 1 May 2003
Schmidt Stephan, Papassotiropoulos Andreas, Sotgiu Stefano, Kölsch Heike, Arru Giannina, Fois Maria Laura, Haase Claus G, Schmitz Sandra, König Nicolaus, Harzheim Michael, Heun Reinhard, Klockgether Thomas
Abstract excerpt
Interleukin-6 (IL-6) plays an important role in the regulation of the inflammatory response in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Previous reports indicated that the C allele of a variable number tandem repeat (vntr) polymorphism located...
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