Article
E-selectin A561C and G98T polymorphisms influence susceptibility and course of multiple sclerosis.
Journal of neuroimmunology - 1 Aug 2005
Galimberti Daniela, Fenoglio Chiara, Clerici Raffaella, Comi Cristoforo, De Riz Milena, Rottoli Mariarosa, Piccio Laura, Ronzoni Marco, Venturelli Eliana, Monaco Francesco, Poloni Marco, Bresolin Nereo, Scarpini Elio
Abstract excerpt
Three hundred seven patients with MS and 300 controls were genotyped for G98T and A561C SNPs in the E-selectin gene, and genetic data were correlated with the course of the disease. The frequency of the T/T genotype of the G98T SNP was significantly increased in RR-MS patients compared with contr...
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