Article
Comparison of tests and procedures to build clinically relevant genotypic scores: application to the Jaguar study.
Antiviral therapy - 1 Jan 2005
Flandre Philippe, Marcelin Anne-Geneviève, Pavie Juliette, Shmidely Nathalie, Wirden Marc, Lada Olivier, Bernard Marie-Charlotte, Molina Jean-Michel, Calvez Vincent
Abstract excerpt
OBJECTIVE: To compare non-parametric tests and procedures of selection in building clinically validated genotypic scores. DESIGN AND PATIENTS: In the Jaguar study, 111 patients on a stable antiretroviral regimen experiencing virological failure were randomized in the didanosine (ddI) arm to receive ddI for 4 weeks in addition to their current combination therapy. METHODS: The virological response was HIV-1 RNA...
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