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Article

Improved interpretation of genotypic changes in the HIV-1 reverse transcriptase coding region that determine the virological response to didanosine.

The Journal of infectious diseases - 1 Dec 2007

De Luca Andrea, Giambenedetto Simona Di, Trotta Maria Paola, Colafigli Manuela, Prosperi Mattia, Ruiz Lidia, Baxter John, Clevenbergh Philippe, Cauda Roberto, Perno Carlo-Federico, Antinori Andrea

Abstract excerpt

BACKGROUND: Consensus on the interpretation of mutations in the human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) gene that predict the response to didanosine treatment is needed. METHODS: Baseline HIV-1 RT genotypes and 12-week virological outcomes for patients undergoing didanosine-containing salvage regimens were extracted from prospective studies. Existing didanosine genotypic-resistance...

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PMID: 18008248
DOI: 10.1086/522231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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