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Article

Clinically relevant genotype interpretation of resistance to didanosine.

Antimicrobial agents and chemotherapy - 1 May 2005

Marcelin Anne-Geneviève, Flandre Philippe, Pavie Juliette, Schmidely Nathalie, Wirden Marc, Lada Olivier, Chiche Dan, Molina Jean-Michel, Calvez Vincent

Abstract excerpt

We analyzed the didanosine (ddI) arm of the randomized, placebo-controlled Jaguar trial in order to define a genotypic score for ddI associated with virologic response. In this arm, 111 patients experiencing virologic failure received ddI in addition to their current combination therapy for 4 weeks. The impact of mutations in the reverse transcriptase gene on the virologic response to ddI was studied in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15855490
DOI: 10.1128/AAC.49.5.1739-1744.2005
PMCID: PMC1087657

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Source receipt: pubmed, retrieved 7 Sept 2026.

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