Article
Scoring methods for building genotypic scores: an application to didanosine resistance in a large derivation set.
PloS one - 1 Jan 2013
Houssaini Allal, Assoumou Lambert, Miller Veronica, Calvez Vincent, Marcelin Anne-Geneviève, Flandre Philippe
Abstract excerpt
BACKGROUND: Several attempts have been made to determine HIV-1 resistance from genotype resistance testing. We compare scoring methods for building weighted genotyping scores and commonly used systems to determine whether the virus of a HIV-infected patient is resistant. METHODS AND PRINCIPAL FINDINGS: Three statistical methods (linear discriminant analysis, support vector machine and logistic regression) are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.