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Clinically validated genotype analysis: guiding principles and statistical concerns.

Antiviral therapy - 1 Aug 2004

Brun-Vézinet Françoise, Costagliola Dominique, Khaled Mounir Ait, Calvez Vincent, Clavel François, Clotet Bonaventura, Haubrich Richard, Kempf Dale, King Marty, Kuritzkes Daniel, Lanier Randall, Miller Michael, Miller Veronica, Phillips Andrews, Pillay Deenan, Schapiro Jonathan, Scott Janna, Shafer Robert, Zazzi Maurizio, Zolopa Andrew, DeGruttola Victor

Abstract excerpt

Whereas previously the output of HIV resistance tests has been based on therapeutically arbitrary criteria, there is now an ongoing move towards correlating test interpretation with virological outcomes on treatment. This approach is undeniably superior, in principle, for tests intended to guide drug choices. However the predictive accuracy of a given stratagem that links genotype or phenotype to drug response is...

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PMID: 15456077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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