Article
Initiatives for developing and comparing genotype interpretation systems: external validation of existing systems for didanosine against virological response.
The Journal of infectious diseases - 15 Aug 2008
Assoumou Lambert, Brun-Vézinet Françoise, Cozzi-Lepri Alessandro, Kuritzkes Daniel, Phillips Andrew, Zolopa Andrew, Degruttola Victor, Miller Veronica, Costagliola Dominique
Abstract excerpt
BACKGROUND: This study was performed to investigate the concordance between commonly used human immunodeficiency virus type 1 (HIV-1) drug resistance interpretation systems for didanosine (ddI) and their ability to predict responses at weeks 8 and 24. METHODS: The study included drug-experienced HIV-infected patients who had viral loads >500 copies/mL and who underwent a genotypic resistance test when beginning a...
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