Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.

doi:10.1158/1055-9965.EPI-04-0807

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2005

Kuschel Bettina, Chenevix-Trench Georgia, Spurdle Amanda B, Chen Xiaoqing, Hopper John L, Giles Graham G, McCredie Margret, Chang-Claude Jenny, Gregory Catherine S, Day Nick E, Easton Douglas F, Ponder Bruce A J, Dunning Alison M, Pharoah Paul D P

Abstract excerpt

A substantial proportion of the familial risk of breast cancer may be due to genetic variants, each contributing a small effect. The protein encoded by ERCC2 is a key enzyme involved in nucleotide excision repair, in which gene defects could lead to cancer prone syndromes such as Xeroderma pigmentosum D. We have examined the association between single nucleotide polymorphisms in the ERCC2 gene and the incidence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to DNA-Binding Proteins

Share to DNA Helicases

Share to Polymorphism, Single Nucleotide

Share to Population Surveillance

Share to Transcription Factors

Share to Xeroderma Pigmentosum Group D Protein

Source

Open in PubMed

Identifiers

PMID: 16030124
DOI: 10.1158/1055-9965.EPI-04-0807

Genes

ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.PMID 16030124Read ↗

Xeroderma pigmentosum group D: Report of a novel combination of ERCC2 variations and its phenotype.Semantic proximity Read ↗

Breast cancer risk is not associated with polymorphic forms of xeroderma pigmentosum genes in a cohort of women from Washington County, Maryland.Semantic proximity Read ↗

A noncancerous variant of xeroderma pigmentosum type D associated with novel heterozygous missense ERCC2 gene mutation.Semantic proximity Read ↗

ERCC2 genotypes and a corresponding haplotype are linked with breast cancer risk in a German population.Semantic proximity Read ↗

Common XPD (ERCC2) polymorphisms have no measurable effect on nucleotide excision repair and basal transcription.Semantic proximity Read ↗

The polymorphism of DNA repair gene ERCC2/XPD Arg156Arg and susceptibility to breast cancer in a Chinese population.Semantic proximity Read ↗

Meta-analysis of two ERCC2 (XPD) polymorphisms, Asp312Asn and Lys751Gln, in breast cancer.Semantic proximity Read ↗

Interethnic variability of ERCC2 polymorphisms.Semantic proximity Read ↗

ERCC2/XPD gene polymorphisms and cancer risk.Semantic proximity Read ↗

Polymorphisms in XPC and ERCC2 genes, smoking and breast cancer risk.Semantic proximity Read ↗

DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk.Semantic proximity Read ↗

Genetic polymorphisms in the DNA repair enzyme ERCC2 and breast tumour risk in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.