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Article

Polymorphisms in XPC and ERCC2 genes, smoking and breast cancer risk.

International journal of cancer - 1 May 2008

Shore Roy E, Zeleniuch-Jacquotte Anne, Currie Diane, Mohrenweiser Harvey, Afanasyeva Yelena, Koenig Karen L, Arslan Alan A, Toniolo Paolo, Wirgin Isaac

Abstract excerpt

To evaluate the associations of breast cancer risk with polymorphisms in the XPC and XPD/ERCC2 DNA nucleotide excision repair genes, a case-control study nested within a prospective cohort of 14,274 women was conducted. Genotypes were characterized for 612 incident, invasive breast cancer cases and their 1:1 matched controls. The homozygous variant of a poly(AT) insertion/deletion polymorphism in intron 9 of the...

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Source

Identifiers

PMID: 18196582
DOI: 10.1002/ijc.23361

Genes

XPC
ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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