Article
Bovine chondrocyte behaviour in three-dimensional type I collagen gel in terms of gel contraction, proliferation and gene expression.
Biomaterials - 1 Jan 2006
Galois Laurent, Hutasse Sandrine, Cortial Delphine, Rousseau Cécile F, Grossin Laurent, Ronziere Marie-Clarie, Herbage Daniel, Freyria Anne-Marie
Abstract excerpt
This study evaluated the in vitro behaviour of bovine chondrocytes seeded in collagen gels, promising recently reported scaffolds for the treatment of full-thickness cartilage defects. To determine how chondrocytes respond to a collagen gel environment, 2 x 10(6) chondrocytes isolated from fetal, calf and adult bovine cartilage were seeded within type I collagen gels and grown for 12 days in both attached and...
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