Article
Adhesion, growth, and matrix production by osteoblasts on collagen substrata.
Calcified tissue international - 1 Sept 1992
Masi L, Franchi A, Santucci M, Danielli D, Arganini L, Giannone V, Formigli L, Benvenuti S, Tanini A, Beghè F
Abstract excerpt
A number of studies have demonstrated the pivotal role of collagen molecules in modulating cell growth and differentiation. In order to analyze the direct effects of collagen type I on the osteoblastic phenotype, we have devised an in vitro culture system for studying the interactions between bov...
Topics
- Alkaline Phosphatase
- Bone Neoplasms
- Cell Adhesion
- Cell Differentiation
- Cell Division
- Cell Transformation, Neoplastic
- Collagen
- Cyclic AMP
- Cytophotometry
- DNA, Neoplasm
- Extracellular Matrix
- Fluorescent Antibody Technique
- Gels
- Humans
- Immunohistochemistry
- Microscopy, Electron
- Osteoblasts
- Osteocalcin