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Article

Human cardiac valve interstitial cells in collagen sponge: a biological three-dimensional matrix for tissue engineering.

The Journal of heart valve disease - 1 May 2002

Taylor Patricia M, Allen Sean P, Dreger Sally A, Yacoub Magdi H

Abstract excerpt

BACKGROUND AND AIM OF STUDY: The use of a biological, biodegradable scaffold remodeled by cells to resemble a valve leaflet is an attractive approach to tissue engineering. The study aim was to evaluate the suitability of a three-dimensional biodegradable collagen sponge for maintenance of cell viability, proliferation and phenotype of cultured human cardiac valve interstitial cells (ICs). METHODS: Pieces of...

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Identifiers

PMID: 12056719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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