Article
Effects of static or dynamic mechanical stresses on osteoblast phenotype expression in three-dimensional contractile collagen gels.
Journal of cellular biochemistry - 1 Dec 1999
Akhouayri O, Lafage-Proust M H, Rattner A, Laroche N, Caillot-Augusseau A, Alexandre C, Vico L
Abstract excerpt
Studies performed at tissular (three-dimensional, 3-D) or cellular (two-dimensional, 2-D) levels showed that the loading pattern plays a crucial role in the osteoblastic physiology. In this study, we attempted to investigate the response of a 3-D osteoblastic culture submitted to either no external stress or static or dynamic stresses. Rat osteosarcoma cells (ROS 17/2.8) were embedded within collagen type I...
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