Article
Cartilaginous constructs using primary chondrocytes from continuous expansion culture seeded in dense collagen gels.
Acta biomaterialia - 1 Dec 2013
Rosenzweig D H, Chicatun F, Nazhat S N, Quinn T M
Abstract excerpt
Cell-based therapies such as autologous chondrocyte implantation require in vitro cell expansion. However, standard culture techniques require cell passaging, leading to dedifferentiation into a fibroblast-like cell type. Primary chondrocytes grown on continuously expanding culture dishes (CE culture) limits passaging and protects against dedifferentiation. The authors tested whether CE culture chondrocytes were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.