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Article

Enhanced chondrogenic phenotype of primary bovine articular chondrocytes in Fibrin-Hyaluronan hydrogel by multi-axial mechanical loading and FGF18.

Acta biomaterialia - 15 Mar 2020

Antunes Bernardo P, Vainieri M Letizia, Alini Mauro, Monsonego-Ornan Efrat, Grad Sibylle, Yayon Avner

Abstract excerpt

Current treatments for cartilage lesions are often associated with fibrocartilage formation and donor site morbidity. Mechanical and biochemical stimuli play an important role in hyaline cartilage formation. Biocompatible scaffolds capable of transducing mechanical loads and delivering bioactive instructive factors may better support cartilage regeneration. In this study we aimed to test the interplay between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31982592
DOI: 10.1016/j.actbio.2020.01.032

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