Article
A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions.
American journal of human genetics - 1 Oct 2003
Seddon Johanna M, Santangelo Susan L, Book Kathryn, Chong Sandy, Cote Jennifer
Abstract excerpt
We report the results of a genomewide scan for age-related macular degeneration (AMD) in 158 multiplex families. AMD classification was based on fundus photography and was assigned a grade ranging from 1 (no disease) to 5 (exudative disease). Genotyping was performed by the National Heart, Lung, and Blood Institute Mammalian Genotyping Service at Marshfield (404 short tandem repeat markers). The sample included...
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