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Article

Genome-wide analyses demonstrate novel loci that predispose to drusen formation.

Investigative ophthalmology & visual science - 1 Sept 2005

Jun Gyungah, Klein Barbara E K, Klein Ronald, Fox Katherine, Millard Christopher, Capriotti Jennifer, Russo Karlie, Lee Kristine E, Elston Robert C, Iyengar Sudha K

Abstract excerpt

PURPOSE: To test whether genes for drusen formation are independent of age-related macular degeneration (AMD) pathogenesis. METHODS: A genome-wide model-free linkage analysis was performed, using two semiquantitative drusen traits, size and type, on two sets of data: (1) 325 individuals (225 sib pairs) from the Beaver Dam Eye Study (BDES), and (2) 297 individuals (346 sib pairs) from the Family Age Related...

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Source

Identifiers

PMID: 16123405
DOI: 10.1167/iovs.04-1360

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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