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Article

Polymorphisms in the DNA methyltransferase 3b gene and prostate cancer risk.

Oncology reports - 1 Aug 2005

Singal Rakesh, Das Partha M, Manoharan Murugesan, Reis Isildinha M, Schlesselman James J

Abstract excerpt

Inactivation of tumor suppressor genes by promoter methylation is an important mechanism of tumorigenesis. Increased expression of DNA methyltransferases has been commonly observed in cancer. A C/T polymorphism in the DNA methyltransferase 3b (DNMT3b) promoter region results in increased activity and has recently been identified as a risk factor for lung cancer. In this study, we examined the C/T polymorphism of...

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PMID: 16012746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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