Article
Genetic Polymorphism of Mismatch Repair Genes and Susceptibility to Prostate Cancer.
Urology journal - 16 May 2020
Khooshemehri Paniz, Jamaldini Seyed Hamid, Ziaee Seyed Amir Mohsen, Afshari Mahdi, Sattari Mahshid, Narouie Behzad, Sotoudeh Mehdi, Montazeri Vahideh, Sarhangi Negar, Hasanzad Mandana
Abstract excerpt
PURPOSE: Mismatch repair (MMR) is one of the DNA repair systems that correct mispaired bases during DNA replication errors. Polymorphisms in genes can increase susceptibility to the development of prostate cancer (PCa). In this study, we investigated mutL homolog 1 (MLH1) -93G>A (rs1800734) and mutS homolog 3 (MSH3) (rs26279) polymorphisms with the risk of PCa. MATERIALS AND METHODS: In this study of Iranian...
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