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Article

Methylation of multiple genes in prostate cancer and the relationship with clinicopathological features of disease

1 Sept 2004

Abstract excerpt

Promoter methylation plays an important role in the inactivation of tumor suppressor genes during tumorigenesis. We examined the methylation status of glutathione s-transferase Pi1 (GSTP1), retinoic acid receptor beta (RARB), CD44, E-cadherin (ECAD), RAS association domain family protein 1A (RASSF1A) and endothelin B receptor (EDNRB) genes in 81 prostate cancer and 42 benign prostatic hyperpasia specimens....

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PMID: 15289848
DOI: 10.3892/or.12.3.631

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