Article
Escherichia coli mutator (Delta)polA is defective in base mismatch correction: the nature of in vivo DNA replication errors.
Journal of molecular biology - 12 Aug 2005
Tago Yu-ichiro, Imai Masaru, Ihara Makoto, Atofuji Hironari, Nagata Yuki, Yamamoto Kazuo
Abstract excerpt
We constructed a set of Escherichia coli strains containing deletions in genes encoding three SOS polymerases, and defective in MutS and DNA polymerase I (PolI) mismatch repair, and estimated the rate and specificity of spontaneous endogenous tonB(+)-->tonB- mutations. The rate and specificity of mutations in strains proficient or deficient in three SOS polymerases was compared and found that there was no...
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