Article
Genomic analysis of metabolic pathway gene expression in mice.
Genome biology - 1 Jan 2005
Ghazalpour Anatole, Doss Sudheer, Sheth Sonal S, Ingram-Drake Leslie A, Schadt Eric E, Lusis Aldons J, Drake Thomas A
Abstract excerpt
BACKGROUND: A segregating population of (C57BL/6J x DBA/2J)F2 intercross mice was studied for obesity-related traits and for global gene expression in liver. Quantitative trait locus analyses were applied to the subcutaneous fat-mass trait and all gene-expression data. These data were then used to identify gene sets that are differentially perturbed in lean and obese mice. RESULTS: We integrated global...
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